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1628448-77-0

1628448-77-0 structure
1628448-77-0 structure
  • Name: GPR120 agonist 4x
  • Chemical Name: GPR120 Agonist 1
  • CAS Number: 1628448-77-0
  • Molecular Formula: C20H12ClF6NO3S
  • Molecular Weight: 495.82
  • Catalog: Signaling Pathways GPCR/G Protein GPR120
  • Create Date: 2019-08-04 02:02:59
  • Modify Date: 2024-01-10 21:36:56
  • GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].

Name GPR120 Agonist 1
Description GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].
Related Catalog
Target

GPR120[1]

In Vitro GPR120 Agonist 1 is a potent and selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human GPR120 and mouse GPR120 (the calcium flux assay), respectively[1].
References

[1]. Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952.

Molecular Formula C20H12ClF6NO3S
Molecular Weight 495.82