2095156-13-9

2095156-13-9 structure

2095156-13-9 structure

Name: HSL-IN-1
Chemical Name: HSL-IN-1
CAS Number: 2095156-13-9
Molecular Formula: C₁₉H₁₃BClF₃N₂O₄
Molecular Weight: 436.58
Catalog: Research Areas Metabolic Disease
Create Date: 2019-08-04 10:20:59
Modify Date: 2024-01-14 15:48:49
HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].

Name	HSL-IN-1

Description	HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: 2 nM (Hormone sensitive lipase)[1]
References	[1]. Ogiyama T, et al. Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243.

Molecular Formula	C₁₉H₁₃BClF₃N₂O₄
Molecular Weight	436.58