2095156-13-9

2095156-13-9 structure
2095156-13-9 structure
  • Name: HSL-IN-1
  • Chemical Name: HSL-IN-1
  • CAS Number: 2095156-13-9
  • Molecular Formula: C19H13BClF3N2O4
  • Molecular Weight: 436.58
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2019-08-04 10:20:59
  • Modify Date: 2024-01-14 15:48:49
  • HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].

Name HSL-IN-1
Description HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].
Related Catalog
Target

IC50: 2 nM (Hormone sensitive lipase)[1]

References

[1]. Ogiyama T, et al. Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243.

Molecular Formula C19H13BClF3N2O4
Molecular Weight 436.58