1246999-33-6

1246999-33-6 structure

Name: Tos-PEG4-NH-Boc
Chemical Name: PROTAC Linker 7
CAS Number: 1246999-33-6
Molecular Formula: C₂₀H₃₃NO₈S
Molecular Weight: 447.54
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-08-03 22:54:59
Modify Date: 2024-01-12 22:32:28
PROTAC Linker 7 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 7 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	PROTAC Linker 7

Description	PROTAC Linker 7 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 7 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.