Tos-PEG4-NH-Boc

Modify Date: 2024-01-12 22:32:28

Tos-PEG4-NH-Boc Structure
Tos-PEG4-NH-Boc structure
Common Name Tos-PEG4-NH-Boc
CAS Number 1246999-33-6 Molecular Weight 447.54
Density N/A Boiling Point N/A
Molecular Formula C20H33NO8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG4-NH-Boc


PROTAC Linker 7 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 7 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 7

 Tos-PEG4-NH-Boc Biological Activity

Description PROTAC Linker 7 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 7 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C20H33NO8S
Molecular Weight 447.54
Storage condition 2-8°C