2296727-52-9
2296727-52-9 structure
- Name: QM385
- Chemical Name: QM385
- CAS Number: 2296727-52-9
- Molecular Formula: C18H19F3N6O2
- Molecular Weight: 408.38
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2019-08-03 17:47:58
- Modify Date: 2025-08-25 11:33:46
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QM385 is a potent sepiapterin reductase (SPR) inhibitor with an IC50 of 1.49 nM, which blocks T-cell proliferation and autoimmunity at nanomolar potency and with good oral bioavailability[1].
| Name | QM385 |
|---|
| Description | QM385 is a potent sepiapterin reductase (SPR) inhibitor with an IC50 of 1.49 nM, which blocks T-cell proliferation and autoimmunity at nanomolar potency and with good oral bioavailability[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.49 nM (Sepiapterin reductase)[1] |
| In Vitro | QM385 effectively inhibits the proliferation of human CD4+ T cells at low doses[1]. |
| References |
| Molecular Formula | C18H19F3N6O2 |
|---|---|
| Molecular Weight | 408.38 |