1941168-63-3

1941168-63-3 structure

Name: MC-Sq-Cit-PAB-Gefitinib
Chemical Name: MC-Sq-Cit-PAB-Gefitinib
CAS Number: 1941168-63-3
Molecular Formula: C₅₀H₆₁ClFN₁₀O₉
Molecular Weight: 1000.53
Catalog: Signaling Pathways Antibody-drug Conjugate Drug-Linker Conjugates for ADC
Create Date: 2019-09-11 17:28:03
Modify Date: 2025-09-23 17:08:05
MC-Sq-Cit-PAB-Gefitinib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Sq-Cit-PAB-Gefitinib is used for the antibody-drug conjugates (ADC) to treat various diseases or disorders, e.g. characterized by the overexpression of a tumor antigen[1,2].

Name	MC-Sq-Cit-PAB-Gefitinib

Description	MC-Sq-Cit-PAB-Gefitinib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Sq-Cit-PAB-Gefitinib is used for the antibody-drug conjugates (ADC) to treat various diseases or disorders, e.g. characterized by the overexpression of a tumor antigen[1,2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
References	[1]. FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1. [2]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

Molecular Formula	C₅₀H₆₁ClFN₁₀O₉
Molecular Weight	1000.53