MC-Sq-Cit-PAB-Gefitinib

Modify Date: 2024-01-11 13:44:32

MC-Sq-Cit-PAB-Gefitinib Structure
MC-Sq-Cit-PAB-Gefitinib structure
Common Name MC-Sq-Cit-PAB-Gefitinib
CAS Number 1941168-63-3 Molecular Weight 1000.53
Density N/A Boiling Point N/A
Molecular Formula C50H61ClFN10O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Sq-Cit-PAB-Gefitinib


MC-Sq-Cit-PAB-Gefitinib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Sq-Cit-PAB-Gefitinib is used for the antibody-drug conjugates (ADC) to treat various diseases or disorders, e.g. characterized by the overexpression of a tumor antigen[1,2].

 Names

Name MC-Sq-Cit-PAB-Gefitinib

 MC-Sq-Cit-PAB-Gefitinib Biological Activity

Description MC-Sq-Cit-PAB-Gefitinib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Sq-Cit-PAB-Gefitinib is used for the antibody-drug conjugates (ADC) to treat various diseases or disorders, e.g. characterized by the overexpression of a tumor antigen[1,2].
Related Catalog
References

[1]. FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.

[2]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

 Chemical & Physical Properties

Molecular Formula C50H61ClFN10O9
Molecular Weight 1000.53