1313730-09-4

1313730-09-4 structure

Name: WKYMVM TFA
Chemical Name: WKYMVM TFA
CAS Number: 1313730-09-4
Molecular Formula: C₄₃H₆₂F₃N₉O₉S₂
Molecular Weight: 970.13
Catalog: Research Areas Inflammation/Immunology
Create Date: 2019-09-07 18:00:16
Modify Date: 2024-01-11 14:53:51
WKYMVM (TFA) is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase[1][2].

Name	WKYMVM TFA

Description	WKYMVM (TFA) is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	FPR1, FPRL1[1], FPRL2[2]
References	[1]. Christophe T, et al. The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem. 2001 Jun 15;276(24):21585-93. [2]. Christophe T, et al. Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4. Scand J Immunol. 2002 Nov;56(5):470-6.

Molecular Formula	C₄₃H₆₂F₃N₉O₉S₂
Molecular Weight	970.13