1632250-50-0
1632250-50-0 structure
- Name: PF-06446846 hydrochloride
- Chemical Name: PF-06446846 hydrochloride
- CAS Number: 1632250-50-0
- Molecular Formula: C22H20ClN7O
- Molecular Weight: 433.893
- Create Date: 2019-09-07 00:01:19
- Modify Date: 2025-09-12 15:11:30
-
PF-06446846 (PF-6446846) is a potent, highly selective inhibitor of PCSK9 translation with IC50 of 0.3 uM for inhibition the secretion of PCSK9 by Huh7 cells.
| Name | PF-06446846 hydrochloride |
|---|---|
| Synonyms |
Benzamide, N-(3-chloro-2-pyridinyl)-N-[(3R)-3-piperidinyl]-4-(3H-1,2,3-triazolo[4,5-b]pyridin-3-yl)-
N-(3-Chloro-2-pyridinyl)-N-[(3R)-3-piperidinyl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 655.5±65.0 °C at 760 mmHg |
| Molecular Formula | C22H20ClN7O |
| Molecular Weight | 433.893 |
| Flash Point | 350.2±34.3 °C |
| Exact Mass | 433.141785 |
| LogP | 1.86 |
| Appearance | powder,white to beige |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.745 |
| Storage condition | room temp |