2022182-58-5

2022182-58-5 structure

Name: Thalidomide-O-amido-C3-NH2
Chemical Name: E3 Ligase Ligand-Linker Conjugates 52 (TFA)
CAS Number: 2022182-58-5
Molecular Formula: C₂₀H₂₁F₃N₄O₈
Molecular Weight: 502.40
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2019-10-08 12:46:52
Modify Date: 2025-09-12 19:14:16
E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) incorporates a CRBN ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) is a PROTAC precursor[1].

Name	E3 Ligase Ligand-Linker Conjugates 52 (TFA)

Description	E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) incorporates a CRBN ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) is a PROTAC precursor[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.

Molecular Formula	C₂₀H₂₁F₃N₄O₈
Molecular Weight	502.40