2349393-21-9

2349393-21-9 structure

2349393-21-9 structure

Name: KRAS G12C inhibitor 15
Chemical Name: KRAS G12C inhibitor 15
CAS Number: 2349393-21-9
Molecular Formula: C₂₅H₂₁ClF₂N₄O₃
Molecular Weight: 498.91
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2019-10-07 21:39:52
Modify Date: 2024-01-09 16:58:37
KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].

Name	KRAS G12C inhibitor 15

Description	KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:5 nM (IC50)
References	[1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

Molecular Formula	C₂₅H₂₁ClF₂N₄O₃
Molecular Weight	498.91