KRAS G12C inhibitor 15

Modify Date: 2024-01-09 16:58:37

KRAS G12C inhibitor 15 Structure
KRAS G12C inhibitor 15 structure
Common Name KRAS G12C inhibitor 15
CAS Number 2349393-21-9 Molecular Weight 498.91
Density N/A Boiling Point N/A
Molecular Formula C25H21ClF2N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KRAS G12C inhibitor 15


KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].

 Names

Name KRAS G12C inhibitor 15

 KRAS G12C inhibitor 15 Biological Activity

Description KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].
Related Catalog
Target

KRas G12C:5 nM (IC50)

References

[1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

 Chemical & Physical Properties

Molecular Formula C25H21ClF2N4O3
Molecular Weight 498.91