KRAS G12C inhibitor 15

Modify Date: 2024-01-09 16:58:37

Use of KRAS G12C inhibitor 15

KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].

Name	KRAS G12C inhibitor 15

Description	KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:5 nM (IC50)
References	[1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

Molecular Formula	C₂₅H₂₁ClF₂N₄O₃
Molecular Weight	498.91