2095690-70-1

2095690-70-1 structure
2095690-70-1 structure
  • Name: IACS-8803
  • Chemical Name: IACS-8803
  • CAS Number: 2095690-70-1
  • Molecular Formula: C20H23FN10O9P2S2
  • Molecular Weight: 692.53
  • Catalog: Signaling Pathways Immunology/Inflammation STING
  • Create Date: 2019-12-08 08:56:54
  • Modify Date: 2024-04-06 12:33:49
  • IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1].

Name IACS-8803
Description IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1].
Related Catalog
Target

STING[1]

In Vivo IACS-8803 shows a superior systemic anti-tumor response in the B16 murine model of melanoma[1].
References

[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

Molecular Formula C20H23FN10O9P2S2
Molecular Weight 692.53