1384082-96-5

1384082-96-5 structure
1384082-96-5 structure
  • Name: (1α,1'S,4β)-Lanabecestat
  • Chemical Name: (1α,1'S,4β)-Lanabecestat
  • CAS Number: 1384082-96-5
  • Molecular Formula: C26H28N4O
  • Molecular Weight: 412.53
  • Catalog: Signaling Pathways Neuronal Signaling Beta-secretase
  • Create Date: 2019-12-08 11:53:19
  • Modify Date: 2025-08-27 15:40:09
  • (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].

Name (1α,1'S,4β)-Lanabecestat
Description (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].
Related Catalog
References

[1]. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1.

Molecular Formula C26H28N4O
Molecular Weight 412.53
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