(1α,1'S,4β)-Lanabecestat

Modify Date: 2025-08-27 15:40:09

(1α,1'S,4β)-Lanabecestat Structure
(1α,1'S,4β)-Lanabecestat structure
Common Name (1α,1'S,4β)-Lanabecestat
CAS Number 1384082-96-5 Molecular Weight 412.53
Density N/A Boiling Point N/A
Molecular Formula C26H28N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (1α,1'S,4β)-Lanabecestat


(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].

 Names

Name (1α,1'S,4β)-Lanabecestat

 (1α,1'S,4β)-Lanabecestat Biological Activity

Description (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].
Related Catalog
References

[1]. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1.

 Chemical & Physical Properties

Molecular Formula C26H28N4O
Molecular Weight 412.53
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Price: ¥2269/10 mM * 1 mL in DMSO

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