2200274-63-9

2200274-63-9 structure

Name: Glucagon receptor antagonists-5
Chemical Name: Glucagon receptor antagonists-5
CAS Number: 2200274-63-9
Molecular Formula: C₃₀H₂₉ClF₃N₃O₃
Molecular Weight: 572.02
Create Date: 2019-12-09 01:27:19
Modify Date: 2024-02-12 19:23:38
Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonists-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1].

Name	Glucagon receptor antagonists-5

Description	Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonists-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1].
Target	Ki: 32 nM (glucagon receptor)[1]
References	[1]. Xu G, et al. Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126668.

Molecular Formula	C₃₀H₂₉ClF₃N₃O₃
Molecular Weight	572.02