1374248-81-3
1374248-81-3 structure
- Name: Atogepant
- Chemical Name: atogepant
- CAS Number: 1374248-81-3
- Molecular Formula: C29H23F6N5O3
- Molecular Weight: 603.515
- Catalog: Signaling Pathways GPCR/G Protein CGRP Receptor
- Create Date: 2020-01-12 09:01:32
- Modify Date: 2026-07-14 09:11:12
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A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine Phase 3 Clinical
| Name | atogepant |
|---|---|
| Synonyms |
AGN-241689）
MK8031. Atogant (S)—N-((3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-cboxamide 7CRV8RR151 (S)—N-((3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-cboxamid Spiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-cboxamide, 1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-2'-oxo-, (3'S) (S)-N-((3S,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-cboxamide MK-8031 (6S)-N-[(3S,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide (S)-N-[(3S,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2-cboxamide Atogant Monohydrate Atogant API (3'S)-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-cboxamide atogepantum (S)-1'-(tert-butyl)-N-((3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-cboxamide (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-2'-oxo-Spiro[6H |
| Description | A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine Phase 3 Clinical |
|---|---|
| References | References View Related Products by Target CGRP Receptor Migraine |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 693.9±55.0 °C at 760 mmHg |
| Molecular Formula | C29H23F6N5O3 |
| Molecular Weight | 603.515 |
| Flash Point | 373.5±31.5 °C |
| Exact Mass | 603.170532 |
| LogP | 4.37 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.624 |