1902954-60-2
1902954-60-2 structure
- Name: Abeprazan
- Chemical Name: Abeprazan
- CAS Number: 1902954-60-2
- Molecular Formula: C19H17F3N2O3S
- Molecular Weight: 410.410
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Proton Pump
- Create Date: 2020-01-11 17:42:15
- Modify Date: 2024-01-13 15:54:37
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Abeprazan is an acid pump inhibitor.
| Name | Abeprazan |
|---|---|
| Synonyms |
1-{5-(2,4-Difluorophenyl)-1-[(3-fluorophenyl)sulfonyl]-4-methoxy-1H-pyrrol-3-yl}-N-methylmethanamine
Abeprazan 1H-Pyrrole-3-methanamine, 5-(2,4-difluorophenyl)-1-[(3-fluorophenyl)sulfonyl]-4-methoxy-N-methyl- |
| Description | Abeprazan is an acid pump inhibitor. |
|---|---|
| Related Catalog | |
| In Vitro | The mechanism of action of Abeprazan is reversibly binding to H+, K+‐ATPase, and, unlike that of PPIs, does not require acidic environment for drug activation[1]. |
| In Vivo | DWP14012 inhibited acid secretion in a dose-dependent manner and the inhibition of gastric acid secretion was equal to or greater than that of vonoprazan, a previously approved P-CAB, in various in vivo studies using pylorus-ligated rats, lumen-perfused rat models and heidenhain pouch dog models[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 497.9±55.0 °C at 760 mmHg |
| Molecular Formula | C19H17F3N2O3S |
| Molecular Weight | 410.410 |
| Flash Point | 254.9±31.5 °C |
| Exact Mass | 410.091187 |
| LogP | 3.89 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.575 |
| Storage condition | 2-8°C |