221139-79-3
221139-79-3 structure
- Name: Mosedipimod
- Chemical Name: Mosedipimod
- CAS Number: 221139-79-3
- Molecular Formula: C39H70O6
- Molecular Weight: 634.969
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2020-01-11 18:21:16
- Modify Date: 2024-01-02 11:51:37
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Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro; attenuates the asthmatic response in an aluminum hydroxide/ovalbumin-induced model of asthma, inhibits hematogenous metastasis of KIGB-5 biliary cancer cell in hamster model. Other Indication Phase 2 Clinical
| Name | Mosedipimod |
|---|---|
| Synonyms |
1-(acetyloxy)-3-(hexadecanoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate
1-Acetoxy-3-(palmitoyloxy)-2-propanyl (9Z,12Z)-9,12-octadecadienoate 9,12-Octadecadienoic acid, 2-(acetyloxy)-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester, (9Z,12Z)- Mosedipimod |
| Description | Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro; attenuates the asthmatic response in an aluminum hydroxide/ovalbumin-induced model of asthma, inhibits hematogenous metastasis of KIGB-5 biliary cancer cell in hamster model. Other Indication Phase 2 Clinical |
|---|---|
| References | References 1. Yoon SY, et al. Immune Netw. 2015 Apr;15(2):100-9. 2. Shin IS, et al. Int Immunopharmacol. 2016 Jan;30:62-68. 3. Shin IS, et al. Int Immunopharmacol. 2014 Jan;18(1):116-23. 4. Kim MH, et al. J Korean Med Sci. 2009 Jun;24(3):474-80. View Related Products by Target Other Targets Other Indication |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 650.6±35.0 °C at 760 mmHg |
| Molecular Formula | C39H70O6 |
| Molecular Weight | 634.969 |
| Flash Point | 257.4±26.0 °C |
| Exact Mass | 634.517212 |
| LogP | 14.67 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.473 |