429653-28-1
429653-28-1 structure
- Name: VU 0038882
- Chemical Name: 2-[5-(2-Furyl)-1H-pyrazol-3-yl]-1-naphthol
- CAS Number: 429653-28-1
- Molecular Formula: C17H12N2O2
- Molecular Weight: 276.289
- Create Date: 2020-01-11 16:37:51
- Modify Date: 2025-08-29 13:47:47
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A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism; prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis.
| Name | 2-[5-(2-Furyl)-1H-pyrazol-3-yl]-1-naphthol |
|---|---|
| Synonyms |
2-[5-(2-Furyl)-1H-pyrazol-3-yl]-1-naphthol
MFCD03016542 1-Naphthalenol, 2-[5-(2-furanyl)-1H-pyrazol-3-yl]- 2-(5-Furan-2-yl-1H-pyrazol-3-yl)-naphthalen-1-ol |
| Description | A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism; prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis. |
|---|---|
| References | References 1. Mike LA, et al. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8206-11. View Related Products by Target Bacterial |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 525.1±45.0 °C at 760 mmHg |
| Molecular Formula | C17H12N2O2 |
| Molecular Weight | 276.289 |
| Flash Point | 271.4±28.7 °C |
| Exact Mass | 276.089874 |
| LogP | 3.81 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.700 |