VU 0038882

Modify Date: 2024-01-24 18:24:24

VU 0038882 Structure
VU 0038882 structure
Common Name VU 0038882
CAS Number 429653-28-1 Molecular Weight 276.289
Density 1.3±0.1 g/cm3 Boiling Point 525.1±45.0 °C at 760 mmHg
Molecular Formula C17H12N2O2 Melting Point N/A
MSDS N/A Flash Point 271.4±28.7 °C

 Use of VU 0038882


A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism; prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis.

 Names

Name 2-[5-(2-Furyl)-1H-pyrazol-3-yl]-1-naphthol
Synonym More Synonyms

 VU 0038882 Biological Activity

Description A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism; prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis.
References References 1. Mike LA, et al. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8206-11. View Related Products by Target Bacterial

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 525.1±45.0 °C at 760 mmHg
Molecular Formula C17H12N2O2
Molecular Weight 276.289
Flash Point 271.4±28.7 °C
Exact Mass 276.089874
LogP 3.81
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.700

 Synonyms

2-[5-(2-Furyl)-1H-pyrazol-3-yl]-1-naphthol
MFCD03016542
1-Naphthalenol, 2-[5-(2-furanyl)-1H-pyrazol-3-yl]-
2-(5-Furan-2-yl-1H-pyrazol-3-yl)-naphthalen-1-ol
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