503294-13-1
503294-13-1 structure
- Name: Dasolampanel [USAN:INN]
- Chemical Name: Dasolampanel
- CAS Number: 503294-13-1
- Molecular Formula: C17H20ClN5O3
- Molecular Weight: 377.825
- Create Date: 2020-01-11 18:02:40
- Modify Date: 2025-08-22 12:57:38
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Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine. Migraine Discontinued
| Name | Dasolampanel |
|---|---|
| Synonyms |
Dasolampanel
3-Isoquinolinecarboxylic acid, 6-[3-chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-, (3S,4aS,6S,8aR)- (3S,4aS,6S,8aR)-6-[3-Chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-3-isoquinolinecarboxylic acid 1P85D6BE9K |
| Description | Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine. Migraine Discontinued |
|---|---|
| References | References 1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10. 2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6. View Related Products by Target iGluR Migraine |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 642.2±65.0 °C at 760 mmHg |
| Molecular Formula | C17H20ClN5O3 |
| Molecular Weight | 377.825 |
| Flash Point | 342.2±34.3 °C |
| Exact Mass | 377.125458 |
| LogP | 1.99 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.605 |