731006-86-3
731006-86-3 structure
- Name: VU0155094
- Chemical Name: Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate
- CAS Number: 731006-86-3
- Molecular Formula: C24H24N2O4S
- Molecular Weight: 436.523
- Catalog: Signaling Pathways GPCR/G Protein mGluR
- Create Date: 2020-01-11 19:17:09
- Modify Date: 2024-02-13 18:01:29
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VU0155094 is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively; displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6).
| Name | Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate |
|---|---|
| Synonyms |
Benzoic acid, 4-[3-[2-[[4-(acetylamino)phenyl]thio]acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-, methyl ester
MFCD04625924 Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate |
| Description | VU0155094 is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively; displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6). |
|---|---|
| References | References 1. Jalan-Sakrikar N, et al. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. View Related Products by Target mGluR |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 667.0±55.0 °C at 760 mmHg |
| Molecular Formula | C24H24N2O4S |
| Molecular Weight | 436.523 |
| Flash Point | 357.2±31.5 °C |
| Exact Mass | 436.145691 |
| LogP | 4.87 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.606 |