936626-07-2

936626-07-2 structure

Name: MK-7288
Chemical Name: (1r,4r)-2'-Methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide
CAS Number: 936626-07-2
Molecular Formula: C₂₂H₃₁N₃O₄
Molecular Weight: 401.499
Create Date: 2020-01-19 21:02:56
Modify Date: 2024-09-13 16:53:56
A novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome; significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials. Sleep Disorder Phase 1 Clinical

Name	(1r,4r)-2'-Methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide
Synonyms	Spiro[cyclohexane-1,5'(7'H)-furo[3,4-b]pyridine]-4-carboxamide, 2'-methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]- (1r,4r)-2'-Methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide

Description	A novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome; significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials. Sleep Disorder Phase 1 Clinical
References	References 1. Sun H, et al. J Clin Pharmacol. 2013 Dec;53(12):1294-302. View Related Products by Target Histamine Receptor Sleep Disorder