1203490-23-6
1203490-23-6 structure
- Name: Ralaniten
- Chemical Name: Ralaniten
- CAS Number: 1203490-23-6
- Molecular Formula: C21H27ClO5
- Molecular Weight: 394.889
- Catalog: Research Areas Cancer
- Create Date: 2020-01-12 13:13:16
- Modify Date: 2025-08-27 11:23:49
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Ralaniten (EPI-506) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer; AR NTD-targeting agents have the potential to overcome shortcomings of current hormonal therapies by inhibiting all forms of AR-mediated transcriptional activity, and as a result, may affect a broader AR population including mutational and splice variant ARs. Prostate Cancer Phase 2 Clinical
| Name | Ralaniten |
|---|---|
| Synonyms |
(2R)-3-[4-(2-{4-[(2S)-3-Chloro-2-hydroxypropoxy]phenyl}-2-propanyl)phenoxy]-1,2-propanediol
1,2-Propanediol, 3-[4-[1-[4-[(2S)-3-chloro-2-hydroxypropoxy]phenyl]-1-methylethyl]phenoxy]-, (2R)- WC830G6O4X MFCD30502912 |
| Description | Ralaniten (EPI-506) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer; AR NTD-targeting agents have the potential to overcome shortcomings of current hormonal therapies by inhibiting all forms of AR-mediated transcriptional activity, and as a result, may affect a broader AR population including mutational and splice variant ARs. Prostate Cancer Phase 2 Clinical |
|---|---|
| References | References 1. Antonarakis ES, et al. Oncologist. 2016 Dec;21(12):1427-1435. View Related Products by Target Estrogen Receptor/ERR Prostate Cancer |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 601.0±55.0 °C at 760 mmHg |
| Molecular Formula | C21H27ClO5 |
| Molecular Weight | 394.889 |
| Flash Point | 317.2±31.5 °C |
| Exact Mass | 394.154694 |
| LogP | 2.98 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.571 |
| Hazard Codes | Xn |
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