1611470-23-5
1611470-23-5 structure
- Name: Mitochonic Acid 35
- Chemical Name: {5-[(3,5-Dimethoxybenzyl)oxy]-1H-indol-3-yl}acetic acid
- CAS Number: 1611470-23-5
- Molecular Formula: C19H19NO5
- Molecular Weight: 341.358
- Catalog: Research Areas Others
- Create Date: 2020-01-11 13:30:55
- Modify Date: 2024-10-05 17:40:14
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A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model.
| Name | {5-[(3,5-Dimethoxybenzyl)oxy]-1H-indol-3-yl}acetic acid |
|---|---|
| Synonyms |
{5-[(3,5-Dimethoxybenzyl)oxy]-1H-indol-3-yl}acetic acid
1H-Indole-3-acetic acid, 5-[(3,5-dimethoxyphenyl)methoxy]- |
| Description | A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model. |
|---|---|
| References | References 1. Shima H, et al. Sci Rep. 2017 May 15;7(1):1884. View Related Products by Target TNF-alpha |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 595.2±45.0 °C at 760 mmHg |
| Molecular Formula | C19H19NO5 |
| Molecular Weight | 341.358 |
| Flash Point | 313.7±28.7 °C |
| Exact Mass | 341.126312 |
| LogP | 2.71 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.638 |