Mitochonic Acid 35

Modify Date: 2023-10-17 23:14:41

Mitochonic Acid 35 Structure
Mitochonic Acid 35 structure
Common Name Mitochonic Acid 35
CAS Number 1611470-23-5 Molecular Weight 341.358
Density 1.3±0.1 g/cm3 Boiling Point 595.2±45.0 °C at 760 mmHg
Molecular Formula C19H19NO5 Melting Point N/A
MSDS N/A Flash Point 313.7±28.7 °C

 Use of Mitochonic Acid 35


A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model.

 Names

Name {5-[(3,5-Dimethoxybenzyl)oxy]-1H-indol-3-yl}acetic acid
Synonym More Synonyms

 Mitochonic Acid 35 Biological Activity

Description A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model.
References References 1. Shima H, et al. Sci Rep. 2017 May 15;7(1):1884. View Related Products by Target TNF-alpha

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 595.2±45.0 °C at 760 mmHg
Molecular Formula C19H19NO5
Molecular Weight 341.358
Flash Point 313.7±28.7 °C
Exact Mass 341.126312
LogP 2.71
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.638

 Synonyms

{5-[(3,5-Dimethoxybenzyl)oxy]-1H-indol-3-yl}acetic acid
1H-Indole-3-acetic acid, 5-[(3,5-dimethoxyphenyl)methoxy]-