1883351-01-6
1883351-01-6 structure
- Name: UPCDC30245
- Chemical Name: UPCDC30245
- CAS Number: 1883351-01-6
- Molecular Formula: C28H38FN5
- Molecular Weight: 463.633
- Catalog: Signaling Pathways Cell Cycle/DNA Damage p97
- Create Date: 2020-01-11 19:39:32
- Modify Date: 2024-04-05 14:03:40
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UPCDC30245 is an allosteric inhibitor of AAA ATPase p97 with IC50 of 27 nM, binds at the junction between the D1 and D2 domains of p97.
| Name | UPCDC30245 |
|---|---|
| Synonyms |
1-[3-(5-Fluoro-1H-indol-2-yl)phenyl]-N-[2-(4-isopropyl-1-piperazinyl)ethyl]-4-piperidinamine
1-Piperazineethanamine, N-[1-[3-(5-fluoro-1H-indol-2-yl)phenyl]-4-piperidinyl]-4-(1-methylethyl)- 1-(3-(5-Fluoro-1H-indol-2-yl)phenyl)-N-(2-(4-isopropylpiperazin-1-yl)ethyl)piperidin-4-amine UPCDC30245 1-(3-(5-Fluoro-1h-Indol-2-Yl)phenyl)piperidin-4-Yl)(2-(4-Isopropyl-Piperazin1-Yl)ethyl)-Carbamate |
| Description | UPCDC30245 is an allosteric inhibitor of AAA ATPase p97 with IC50 of 27 nM, binds at the junction between the D1 and D2 domains of p97. |
|---|---|
| References | References 1. Segura-Cabrera A, et al. Sci Rep. 2017 Mar 21;7:44912. 2. Banerjee S, et al. Science. 2016 Feb 19;351(6275):871-5. View Related Products by Target p97/VCP |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 647.6±55.0 °C at 760 mmHg |
| Melting Point | 647.6 °C |
| Molecular Formula | C28H38FN5 |
| Molecular Weight | 463.633 |
| Flash Point | 345.4±31.5 °C |
| Exact Mass | 463.311127 |
| LogP | 4.56 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.641 |
| Storage condition | 2-8°C |
| Hazard Codes | Xi |
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