2089389-15-9
2089389-15-9 structure
- Name: (R)-ZINC 3573
- Chemical Name: (R)-ZINC-3573
- CAS Number: 2089389-15-9
- Molecular Formula: C18H21N5
- Molecular Weight: 307.393
- Catalog: Research Areas Infection
- Create Date: 2020-01-11 21:12:01
- Modify Date: 2024-01-07 23:06:39
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(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
| Name | (R)-ZINC-3573 |
|---|---|
| Synonyms |
(R)-ZINC-3573
3-Pyrrolidinamine, N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-, (3R)- (3R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine (R)-ZINC72453573 (R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine |
| Description | (R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release. |
|---|---|
| References | References 1. Lansu K, et al. Nat Chem Biol. 2017 May;13(5):529-536. View Related Products by Target Other Targets |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C18H21N5 |
| Molecular Weight | 307.393 |
| Exact Mass | 307.179688 |
| LogP | 1.36 |
| Index of Refraction | 1.671 |
| Storage condition | 2-8°C |