(R)-ZINC 3573

Modify Date: 2024-01-07 23:06:39

(R)-ZINC 3573 Structure
(R)-ZINC 3573 structure
Common Name (R)-ZINC 3573
CAS Number 2089389-15-9 Molecular Weight 307.393
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H21N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-ZINC 3573


(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.

 Names

Name (R)-ZINC-3573
Synonym More Synonyms

 (R)-ZINC 3573 Biological Activity

Description (R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
References References 1. Lansu K, et al. Nat Chem Biol. 2017 May;13(5):529-536. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C18H21N5
Molecular Weight 307.393
Exact Mass 307.179688
LogP 1.36
Index of Refraction 1.671
Storage condition 2-8°C

 Synonyms

(R)-ZINC-3573
3-Pyrrolidinamine, N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-, (3R)-
(3R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine
(R)-ZINC72453573
(R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine