422554-26-5
422554-26-5 structure
- Name: N-aryl benzimidazole
- Chemical Name: N-(2-Chlorobenzyl)-1-(3-methylphenyl)-1H-benzimidazole-5-carboxamide
- CAS Number: 422554-26-5
- Molecular Formula: C22H18ClN3O
- Molecular Weight: 375.851
- Create Date: 2020-01-11 18:04:58
- Modify Date: 2025-08-25 14:28:14
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N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.
| Name | N-(2-Chlorobenzyl)-1-(3-methylphenyl)-1H-benzimidazole-5-carboxamide |
|---|---|
| Synonyms |
1H-Benzimidazole-5-carboxamide, N-[(2-chlorophenyl)methyl]-1-(3-methylphenyl)-
N-(2-Chlorobenzyl)-1-(3-methylphenyl)-1H-benzimidazole-5-carboxamide MFCD15095628 |
| Description | N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells. |
|---|---|
| References | References 1. Tardiff DF, et al. Science. 2013 Nov 22;342(6161):979-83. View Related Products by Target Other Targets |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C22H18ClN3O |
| Molecular Weight | 375.851 |
| Exact Mass | 375.113831 |
| LogP | 5.41 |
| Index of Refraction | 1.652 |