459168-97-9
459168-97-9 structure
- Name: MJN-228
- Chemical Name: MJN228
- CAS Number: 459168-97-9
- Molecular Formula: C20H20N4O3
- Molecular Weight: 364.398
- Catalog: Research Areas Metabolic Disease
- Create Date: 2020-01-12 00:02:12
- Modify Date: 2025-08-31 06:04:30
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MJN-228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1); shows no affinity for other arachidonoyl probe-protein interactions in HEK293T cell lysate; a probe used to elucidate the role of NUCB1 in lipid metabolic pathways in cells.
| Name | MJN228 |
|---|---|
| Synonyms |
(4-Methyl-1-piperazinyl)(5-nitro-3-phenyl-1H-indol-2-yl)methanone
MJN228 Methanone, (4-methyl-1-piperazinyl)(5-nitro-3-phenyl-1H-indol-2-yl)- |
| Description | MJN-228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1); shows no affinity for other arachidonoyl probe-protein interactions in HEK293T cell lysate; a probe used to elucidate the role of NUCB1 in lipid metabolic pathways in cells. |
|---|---|
| References | References 1. Niphakis MJ, et al. Cell. 2015 Jun 18;161(7):1668-80. View Related Products by Target Other Targets |
| Density | 1.3±0.0 g/cm3 |
|---|---|
| Boiling Point | 629.8±0.0 °C at 760 mmHg |
| Molecular Formula | C20H20N4O3 |
| Molecular Weight | 364.398 |
| Flash Point | 334.7±0.0 °C |
| Exact Mass | 364.153534 |
| LogP | 1.75 |
| Vapour Pressure | 0.0±0.0 mmHg at 25°C |
| Index of Refraction | 1.675 |