883791-50-2
883791-50-2 structure
- Name: R-360163
- Chemical Name: MFCD00614570
- CAS Number: 883791-50-2
- Molecular Formula: C20H16N4O5
- Molecular Weight: 392.365
- Create Date: 2020-01-11 22:01:52
- Modify Date: 2025-08-25 12:39:01
-
R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
| Name | MFCD00614570 |
|---|---|
| Synonyms |
Benzoic acid, 3-[[2-[(2Z)-2-[1,2-dihydro-2-oxo-1-(2-propen-1-yl)-3H-indol-3-ylidene]hydrazinyl]-1,2-dioxoethyl]amino]-
3-({[(2Z)-2-(1-Allyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino](oxo)acetyl}amino)benzoic acid MFCD00614570 |
| Description | R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively. |
|---|---|
| References | References 1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11. View Related Products by Target Beta-catenin |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H16N4O5 |
| Molecular Weight | 392.365 |
| Exact Mass | 392.112061 |
| LogP | 2.62 |
| Index of Refraction | 1.669 |