1434873-26-3
1434873-26-3 structure
- Name: BR103
- Chemical Name: BR103
- CAS Number: 1434873-26-3
- Molecular Formula: C24H28N6O3
- Molecular Weight: 448.527
- Catalog: Signaling Pathways Immunology/Inflammation Complement System
- Create Date: 2020-01-12 09:32:49
- Modify Date: 2024-01-05 15:32:10
-
BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats.
| Name | BR103 |
|---|
| Description | BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats. |
|---|---|
| References | References 1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351. View Related Products by Target Complement System |
| Molecular Formula | C24H28N6O3 |
|---|---|
| Molecular Weight | 448.527 |