BR103
Modify Date: 2025-08-26 16:57:58
BR103 structure
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Common Name | BR103 | ||
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| CAS Number | 1434873-26-3 | Molecular Weight | 448.527 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H28N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BR103BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats. |
| Name | BR103 |
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| Description | BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats. |
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| References | References 1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351. View Related Products by Target Complement System |
| Molecular Formula | C24H28N6O3 |
|---|---|
| Molecular Weight | 448.527 |
| InChIKey | RFBOIZXPIAOMAX-SFHVURJKSA-N |
| SMILES | Cc1[nH]c(C(c2ccccc2)c2ccccc2)nc1C(=O)NC(CCCN=C(N)N)C(=O)O |