1474022-02-0
1474022-02-0 structure
- Name: PF-05381941
- Chemical Name: PF-05381941
- CAS Number: 1474022-02-0
- Molecular Formula: C27H26N6O2
- Molecular Weight: 466.545
- Catalog: Signaling Pathways MAPK/ERK Pathway MAP3K
- Create Date: 2020-01-12 18:07:01
- Modify Date: 2024-07-14 17:09:31
-
PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM.
| Name | PF-05381941 |
|---|
| Description | PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM. |
|---|---|
| References | References 1. Kilty I, et al. Future Med Chem. 2015;7(1):23-33. View Related Products by Target TAK1 |
| Molecular Formula | C27H26N6O2 |
|---|---|
| Molecular Weight | 466.545 |