PF-05381941
Modify Date: 2024-07-14 17:09:31
PF-05381941 structure
|
Common Name | PF-05381941 | ||
|---|---|---|---|---|
| CAS Number | 1474022-02-0 | Molecular Weight | 466.545 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H26N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-05381941PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM. |
| Name | PF-05381941 |
|---|
| Description | PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM. |
|---|---|
| References | References 1. Kilty I, et al. Future Med Chem. 2015;7(1):23-33. View Related Products by Target TAK1 |
| Molecular Formula | C27H26N6O2 |
|---|---|
| Molecular Weight | 466.545 |