263248-16-4
263248-16-4 structure
- Name: TAK-802
- Chemical Name: TAK-802
- CAS Number: 263248-16-4
- Molecular Formula: C26H29FN2O2
- Molecular Weight: 420.528
- Create Date: 2020-01-20 16:15:57
- Modify Date: 2024-02-07 08:13:21
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A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM; exhibits high selectivity for acetylcholinesterase inhibition over butyrylcholinesterase inhibition; increases rhythmic bladder contractions in Guinea pigs and rats without affecting the basal intravesical pressure. Other Indication Phase 2 Discontinued
| Name | TAK-802 |
|---|
| Description | A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM; exhibits high selectivity for acetylcholinesterase inhibition over butyrylcholinesterase inhibition; increases rhythmic bladder contractions in Guinea pigs and rats without affecting the basal intravesical pressure. Other Indication Phase 2 Discontinued |
|---|---|
| References | References 1. Ishichi Y, et al. Bioorg Med Chem. 2005 Mar 15;13(6):1901-11. 2. Nagabukuro H, et al. Eur J Pharmacol. 2004 Feb 6;485(1-3):299-305. 3. Nagabukuro H, et al. Eur J Pharmacol. 2004 Jun 28;494(2-3):225-32. View Related Products by Target Acetylcholinesterase (AChE) Other Indication |
| Molecular Formula | C26H29FN2O2 |
|---|---|
| Molecular Weight | 420.528 |