838842-80-1
838842-80-1 structure
- Name: LDN-76070
- Chemical Name: LDN-76070
- CAS Number: 838842-80-1
- Molecular Formula: C18H17BrFNO4
- Molecular Weight: 410.239
- Create Date: 2020-01-11 18:11:51
- Modify Date: 2024-09-08 17:14:09
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LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).
| Name | LDN-76070 |
|---|
| Description | LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg). |
|---|---|
| References | References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. 2. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18. View Related Products by Target SMN2 Modulator |
| Molecular Formula | C18H17BrFNO4 |
|---|---|
| Molecular Weight | 410.239 |