LDN-76070

Modify Date: 2025-08-26 09:34:08

LDN-76070 Structure
LDN-76070 structure
Common Name LDN-76070
CAS Number 838842-80-1 Molecular Weight 410.239
Density N/A Boiling Point N/A
Molecular Formula C18H17BrFNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LDN-76070


LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).

 Names

Name LDN-76070

 LDN-76070 Biological Activity

Description LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).
References References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. 2. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18. View Related Products by Target SMN2 Modulator

 Chemical & Physical Properties

Molecular Formula C18H17BrFNO4
Molecular Weight 410.239
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