904448-58-4
904448-58-4 structure
- Name: USP10-IN-3
- Chemical Name: USP10-IN-3
- CAS Number: 904448-58-4
- Molecular Formula: C23H32ClN3O
- Molecular Weight: 401.979
- Create Date: 2020-01-11 19:09:53
- Modify Date: 2025-08-25 15:11:42
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USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
| Name | USP10-IN-3 |
|---|
| Description | USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3. |
|---|---|
| References | References 1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215. View Related Products by Target Deubiquitinase (DUB) |
| Molecular Formula | C23H32ClN3O |
|---|---|
| Molecular Weight | 401.979 |