USP10-IN-3
Modify Date: 2025-08-25 15:11:42
USP10-IN-3 structure
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Common Name | USP10-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 904448-58-4 | Molecular Weight | 401.979 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H32ClN3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of USP10-IN-3USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3. |
| Name | USP10-IN-3 |
|---|
| Description | USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3. |
|---|---|
| References | References 1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215. View Related Products by Target Deubiquitinase (DUB) |
| Molecular Formula | C23H32ClN3O |
|---|---|
| Molecular Weight | 401.979 |