1207195-45-6
1207195-45-6 structure
- Name: SR-16835
- Chemical Name: SR-16835
- CAS Number: 1207195-45-6
- Molecular Formula: C26H30N2O
- Molecular Weight: 386.54
- Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
- Create Date: 2020-01-11 18:58:51
- Modify Date: 2023-10-17 15:07:15
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SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM); does not produce conditioned place preference (CPP) alone, but attenuates morphine CPP; shows antiallodynic activity in mice model of chronic pain.
| Name | SR-16835 |
|---|
| Description | SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM); does not produce conditioned place preference (CPP) alone, but attenuates morphine CPP; shows antiallodynic activity in mice model of chronic pain. |
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| References | References 1. Toll L, et al. J Pharmacol Exp Ther. 2009 Dec;331(3):946-53. 2. Khroyan TV, et al. J Pharmacol Exp Ther. 2011 Nov;339(2):687-93. View Related Products by Target Opioid Receptor |
| Molecular Formula | C26H30N2O |
|---|---|
| Molecular Weight | 386.54 |