1235406-03-7
1235406-03-7 structure
- Name: PF-05150122
- Chemical Name: PF-05150122
- CAS Number: 1235406-03-7
- Molecular Formula: C19H10ClF4N5O3S2
- Molecular Weight: 531.885
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
- Create Date: 2020-01-12 10:56:51
- Modify Date: 2024-04-03 16:46:20
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PF-05150122 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. Pain Phase 1 Discontinued
| Name | PF-05150122 |
|---|
| Description | PF-05150122 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. Pain Phase 1 Discontinued |
|---|---|
| References | References 1. Swain NA, et al. J Med Chem. 2017 Aug 24;60(16):7029-7042. 2. Jones HM, et al. Clin Pharmacokinet. 2016 Jul;55(7):875-87. View Related Products by Target Sodium Channel Pain |
| Molecular Formula | C19H10ClF4N5O3S2 |
|---|---|
| Molecular Weight | 531.885 |