PF-05150122
Modify Date: 2024-04-03 16:46:20
PF-05150122 structure
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Common Name | PF-05150122 | ||
|---|---|---|---|---|
| CAS Number | 1235406-03-7 | Molecular Weight | 531.885 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H10ClF4N5O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-05150122PF-05150122 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. Pain Phase 1 Discontinued |
| Name | PF-05150122 |
|---|
| Description | PF-05150122 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. Pain Phase 1 Discontinued |
|---|---|
| References | References 1. Swain NA, et al. J Med Chem. 2017 Aug 24;60(16):7029-7042. 2. Jones HM, et al. Clin Pharmacokinet. 2016 Jul;55(7):875-87. View Related Products by Target Sodium Channel Pain |
| Molecular Formula | C19H10ClF4N5O3S2 |
|---|---|
| Molecular Weight | 531.885 |
| InChIKey | ZAGGUCLXSCVDCK-UHFFFAOYSA-N |
| SMILES | O=S(=O)(Nc1nncs1)c1cc(Cl)c(Oc2ccc(C(F)(F)F)cc2-c2ccnnc2)cc1F |