1377615-76-3
1377615-76-3 structure
- Name: LY3027788
- Chemical Name: LY3027788
- CAS Number: 1377615-76-3
- Molecular Formula: C25H31F2NO11S
- Molecular Weight: 591.576
- Catalog: Signaling Pathways GPCR/G Protein mGluR
- Create Date: 2020-01-20 10:27:56
- Modify Date: 2024-09-05 18:04:39
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A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively; augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds.
| Name | LY3027788 |
|---|
| Description | A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively; augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds. |
|---|---|
| References | References 1. Witkin JM, et al. J Pharmacol Exp Ther. 2017 Apr;361(1):68-86. View Related Products by Target mGluR |
| Molecular Formula | C25H31F2NO11S |
|---|---|
| Molecular Weight | 591.576 |