LY3027788

Modify Date: 2024-09-05 18:04:39

LY3027788 Structure
LY3027788 structure
Common Name LY3027788
CAS Number 1377615-76-3 Molecular Weight 591.576
Density N/A Boiling Point N/A
Molecular Formula C25H31F2NO11S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY3027788


A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively; augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds.

 Names

Name LY3027788

 LY3027788 Biological Activity

Description A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively; augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds.
References References 1. Witkin JM, et al. J Pharmacol Exp Ther. 2017 Apr;361(1):68-86. View Related Products by Target mGluR

 Chemical & Physical Properties

Molecular Formula C25H31F2NO11S
Molecular Weight 591.576
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