1414586-62-1
1414586-62-1 structure
- Name: NSC 45576
- Chemical Name: NSC 45576
- CAS Number: 1414586-62-1
- Molecular Formula: C20H14N2O4S
- Molecular Weight: 378.402
- Create Date: 2020-01-14 09:28:42
- Modify Date: 2025-09-18 11:25:40
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NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM; inhibits cAMP-induced EPAC activation while not affecting PKA activity; a valuable pharmacological tools for elucidating the biological functions of EPAC and for promoting an understanding of disease mechanisms related to EPAC/cAMP signaling.
| Name | NSC 45576 |
|---|
| Description | NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM; inhibits cAMP-induced EPAC activation while not affecting PKA activity; a valuable pharmacological tools for elucidating the biological functions of EPAC and for promoting an understanding of disease mechanisms related to EPAC/cAMP signaling. |
|---|---|
| References | References 1. Tsalkova T, et al. PLoS One. 2012;7(1):e30441. 2. Chen H, et al. J Med Chem. 2014 May 8;57(9):3651-65. 3. Mizuta K, et al. Respir Res. 2013 Sep 2;14:89. View Related Products by Target Other Targets |
| Molecular Formula | C20H14N2O4S |
|---|---|
| Molecular Weight | 378.402 |