1482293-92-4
1482293-92-4 structure
- Name: ABP 1
- Chemical Name: ABP 1
- CAS Number: 1482293-92-4
- Molecular Formula: C13H16N6O6S
- Molecular Weight: 384.367
- Create Date: 2020-01-14 15:19:07
- Modify Date: 2024-01-06 12:54:31
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A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro; covalently labels not only for canonical E1s (UBE1, SAE1/SAE2, NAE1/UBA3, UBE1L, and UBA6) but also for noncanonical E1s (UBA5 and ATG7).
| Name | ABP 1 |
|---|
| Description | A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro; covalently labels not only for canonical E1s (UBE1, SAE1/SAE2, NAE1/UBA3, UBE1L, and UBA6) but also for noncanonical E1s (UBA5 and ATG7). |
|---|---|
| References | References 1. An H, et al. J Am Chem Soc. 2013 Nov 13;135(45):16948-62. 2. An H, et al. Chem Sci. 2015 Sep 1;6(9):5235-5245. View Related Products by Target Ubiquitin-activating Enzyme (E1) |
| Molecular Formula | C13H16N6O6S |
|---|---|
| Molecular Weight | 384.367 |