ABP 1

Modify Date: 2024-01-06 12:54:31

ABP 1 Structure
ABP 1 structure
Common Name ABP 1
CAS Number 1482293-92-4 Molecular Weight 384.367
Density N/A Boiling Point N/A
Molecular Formula C13H16N6O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ABP 1


A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro; covalently labels not only for canonical E1s (UBE1, SAE1/SAE2, NAE1/UBA3, UBE1L, and UBA6) but also for noncanonical E1s (UBA5 and ATG7).

 Names

Name ABP 1

 ABP 1 Biological Activity

Description A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro; covalently labels not only for canonical E1s (UBE1, SAE1/SAE2, NAE1/UBA3, UBE1L, and UBA6) but also for noncanonical E1s (UBA5 and ATG7).
References References 1. An H, et al. J Am Chem Soc. 2013 Nov 13;135(45):16948-62. 2. An H, et al. Chem Sci. 2015 Sep 1;6(9):5235-5245. View Related Products by Target Ubiquitin-activating Enzyme (E1)

 Chemical & Physical Properties

Molecular Formula C13H16N6O6S
Molecular Weight 384.367